[HTML][HTML] Sequence and Functional Characterization of a Renal Sodium/Dicarboxylate Cotransporter (∗)

AM Pajor - Journal of Biological Chemistry, 1995 - ASBMB
The cDNA coding for a rabbit renal Na+/dicarboxylate cotransporter, designated NaDC-1,
was isolated by functional expression in Xenopus oocytes. NaDC-1 cDNA is approximately
2.3 kilobases in length and codes for a protein of 593 amino acids. NaDC-1 protein contains
eight putative transmembrane domains, and the sequence and secondary structure are
related to the renal Na+/sulfate transporter, NaSi-1. Northern analysis shows that the NaDC-
1 message is abundant in kidney and small intestine, and related transporters may be found …