Regulation of isotype switching
D Vercelli, RS Geha - Current opinion in immunology, 1992 - Elsevier
D Vercelli, RS Geha
Current opinion in immunology, 1992•ElsevierIn the past year, our understanding of the mechanisms that regulate isotype switching has
significantly progressed. Activation of germ line transcription by isotype-specific cytokines is
emerging as a crucial mechanism for increasing the accessibility of a particular switch
region, and targeting switch recombination.
significantly progressed. Activation of germ line transcription by isotype-specific cytokines is
emerging as a crucial mechanism for increasing the accessibility of a particular switch
region, and targeting switch recombination.
Abstract
In the past year, our understanding of the mechanisms that regulate isotype switching has significantly progressed. Activation of germ line transcription by isotype-specific cytokines is emerging as a crucial mechanism for increasing the accessibility of a particular switch region, and targeting switch recombination.
Elsevier