RENAL K+ CHANNELS: Structure and Function
W Wang, SC Hebert, G Giebisch - Annual Review of Physiology, 1997 - annualreviews.org
W Wang, SC Hebert, G Giebisch
Annual Review of Physiology, 1997•annualreviews.org▪ Abstract The activity of potassium (K+) channels is intimately linked to several important
transport functions in renal tubules. We review recent progress concerning the properties,
site along the nephron, and physiological regulation of native K+ channels, and compare
their characteristics with those of recently cloned K+ channels. We do not fully cover work on
K+ channels in amphibian tubules, cell cultures, and single tubule cells and do not review
K+ channels in mesangial cells.
transport functions in renal tubules. We review recent progress concerning the properties,
site along the nephron, and physiological regulation of native K+ channels, and compare
their characteristics with those of recently cloned K+ channels. We do not fully cover work on
K+ channels in amphibian tubules, cell cultures, and single tubule cells and do not review
K+ channels in mesangial cells.
▪ Abstract
The activity of potassium (K+) channels is intimately linked to several important transport functions in renal tubules. We review recent progress concerning the properties, site along the nephron, and physiological regulation of native K+ channels, and compare their characteristics with those of recently cloned K+ channels. We do not fully cover work on K+ channels in amphibian tubules, cell cultures, and single tubule cells and do not review K+ channels in mesangial cells.
Annual Reviews