Tumor necrosis factor-α is elevated in plasma and amniotic fluid of patients with severe preeclampsia

MJ Kupferminc, AM Peaceman, TR Wigton… - American journal of …, 1994 - Elsevier
OBJECTIVE: Our purpose was to investigate whether markers for activation of the immune
system are present in patients with preeclampsia by assessing maternal plasma and
amniotic fluid for tumor necrosis factor-α and interleukin-1β. STUDY DESIGN: Twenty-one
patients with severe preeclampsia composed the study group (group A). An antepartum
comparison group was composed of healthy nulliparous patients not in labor and matched
for gestational age (group B). Another control group consisted of term nulliparous patients in …