Stimulus-dependent differences in superoxide anion generation by normal human eosinophils and neutrophils

JB Sedgwick, RF Vrtis, MF Gourley… - Journal of allergy and …, 1988 - Elsevier
The role of eosinophils in allergic and hypersensitivity diseases has yet to be fully
established and remains limited by techniques to isolate the eosinophil in high purity.
Consequently, most studies that evaluate and characterize eosinophil function are
conducted with isolates from patients with hypereosinophilia. There is, however, evidence to
suggest that isolates from such patients do not represent normal function. Now, with new
techniques to isolate and purify eosinophils from normal subjects without eosinophilia …