Aldose and aldehyde reductases from human kidney cortex and medulla
B Robinson, LA Hunsaker, LA Stangebye… - … et Biophysica Acta (BBA …, 1993 - Elsevier
Aldose reductase and aldehyde reductase were purified to homogeneity from multiple
samples of human kidney cortex and medulla. A single form of aldose reductase is
expressed in kidney that is kinetically and immunochemically indistinguishable from aldose
reductase expressed in other human tissues. The results support the conclusion that there is
a single human aldose reductase, and that aldose reductase is expressed in a reduced
from, characterized by high sensitivity to aldose reductase inhibitors and ability to catalyze …
samples of human kidney cortex and medulla. A single form of aldose reductase is
expressed in kidney that is kinetically and immunochemically indistinguishable from aldose
reductase expressed in other human tissues. The results support the conclusion that there is
a single human aldose reductase, and that aldose reductase is expressed in a reduced
from, characterized by high sensitivity to aldose reductase inhibitors and ability to catalyze …