Increases in oxygen tension evoke arteriolar constriction by inhibiting endothelial prostaglandin synthesis
EJ Messina, D Sun, A Koller, MS Wolin, G Kaley - Microvascular research, 1994 - Elsevier
In vivo and in vitro studies concerned with the role of oxygen in the regulation of blood flow
have primarily investigated the response of blood vessels to decreases in oxygen tension. In
this study, we examined the response of isolated rat cremaster skeletal muscle arterioles to
increases in oxygen tensions. First-order arterioles with an average diameter of 90 μm were
cannulated and pressurized to 65 mm Hg and studied under constant pressure in a no-flow
state. Arterioles were equilibrated in a Krebs bicarbonate-buffered solution (ph 7.4) gassed …
have primarily investigated the response of blood vessels to decreases in oxygen tension. In
this study, we examined the response of isolated rat cremaster skeletal muscle arterioles to
increases in oxygen tensions. First-order arterioles with an average diameter of 90 μm were
cannulated and pressurized to 65 mm Hg and studied under constant pressure in a no-flow
state. Arterioles were equilibrated in a Krebs bicarbonate-buffered solution (ph 7.4) gassed …