Publisher Summary This chapter attempts an interdisciplinary perspective to consider that
that both molecular biologists and immunologists have learned about the V (D) J
recombination process, as instructed by cross-species (and cross-locus) comparisons.
Immune recognition in vertebrates is based on the antigen receptors manufactured by B and
T cells. The antigen-binding polypeptides within these multiunit conglomerates are encoded
at the immunoglobulin (Ig) and T cell receptor (TCR) loci. Through the process called “V (D) …