Chemokines in the cerebrospinal fluid of patients with meningitis
H Sprenger, A Rösler, P Tonn, HJ Braune… - Clinical immunology and …, 1996 - Elsevier
Meningitis is accompanied by a differential immigration of leukocytes into the subarachnoid
space. Since the mechanisms regulating leukocyte invasion are still incompletely
understood, we studied the release of the neutrophil-attracting α-chemokines IL-8 and GRO-
α and the mononuclear cell-attracting β-chemokines MCP-1, MIP-1α, and RANTES during
meningitis. In 48 paired CSF and serum samples from patients hospitalized for meningitic
symptoms, high levels of IL-8, GRO-α, and MCP-1 were detected in the CSF during bacterial …
space. Since the mechanisms regulating leukocyte invasion are still incompletely
understood, we studied the release of the neutrophil-attracting α-chemokines IL-8 and GRO-
α and the mononuclear cell-attracting β-chemokines MCP-1, MIP-1α, and RANTES during
meningitis. In 48 paired CSF and serum samples from patients hospitalized for meningitic
symptoms, high levels of IL-8, GRO-α, and MCP-1 were detected in the CSF during bacterial …