Chemokine expression in murine experimental allergic encephalomyelitis
R Godiska, D Chantry, GN Dietsch, PW Gray - Journal of neuroimmunology, 1995 - Elsevier
Chemokines are a family of low molecular mass proteins with chemotactic and cell activating
activities. Reverse transcription-polymerase chain reaction and Northern hybridization were
used to examine their expression during murine experimental allergic encephalomyelitis
(EAE), an autoimmune disease used as a model of multiple sclerosis. The mRNAs encoding
RANTES, MIP-1α, MIP1β, TCA3 (1–309), IP-10, JE (MCP-1), KC (MGSA/gro), and MARC
(MCP-3) were induced in the spinal cord 1–2 days before clinical signs were apparent, SDP …
activities. Reverse transcription-polymerase chain reaction and Northern hybridization were
used to examine their expression during murine experimental allergic encephalomyelitis
(EAE), an autoimmune disease used as a model of multiple sclerosis. The mRNAs encoding
RANTES, MIP-1α, MIP1β, TCA3 (1–309), IP-10, JE (MCP-1), KC (MGSA/gro), and MARC
(MCP-3) were induced in the spinal cord 1–2 days before clinical signs were apparent, SDP …