* Compared with meal alone. Soh= solution; LA wine= low-alcohol wine; MCT= medium-chain triglycerides. feeding-induced release of gastrin, pancreatic polypeptide, and somatostatin. Acute mental stress inhibits gastric and pancreatic exocrine secretion in humans (25). In volunteers who had earlier participated in physiologic studies of gastric and pancreatic secretion, placement of a nasogastric tube did not alter cardiovascular indicators of stress (26), suggesting that repeated stress led to a tolerance of its physiologic effects. There are, however, no studies to show that gastric and pancreatic responses differ in ‘professional’swallowers compared with in tube-naive volunteers. In any case, it would be advisable to randomize the order in which the tests are conducted so that not all subjects start the series of studies with a particular test solution. It would probably also be advisable to choose subjects who are either all tubenaive or have all had previous experience of gastrointestinal intubations.