[HTML][HTML] Neurons can maintain multiple classes of nicotinic acetylcholine receptors distinguished by different subunit compositions (∗)
WG Conroy, DK Berg - Journal of Biological Chemistry, 1995 - ASBMB
Although 10 genes have been cloned encoding putative subunits of neuronal nicotinic
acetylcholine receptors, little is known about the variety or subunit composition of such
receptors expressed by individual neurons. Chick ciliary ganglion neurons express five of
the known genes and assemble a class of synaptic-type receptors collectively containing
gene products from three of them: α3, β4, and α5. Using subunit-specific monoclonal
antibodies, we show here that all of the synaptic-type acetylcholine receptors having α3 also …
acetylcholine receptors, little is known about the variety or subunit composition of such
receptors expressed by individual neurons. Chick ciliary ganglion neurons express five of
the known genes and assemble a class of synaptic-type receptors collectively containing
gene products from three of them: α3, β4, and α5. Using subunit-specific monoclonal
antibodies, we show here that all of the synaptic-type acetylcholine receptors having α3 also …