Partial enzyme deficiencies: residual activities and the development of neurological disorders
E Conzelmann, K Sandhoff - Developmental neuroscience, 1983 - karger.com
E Conzelmann, K Sandhoff
Developmental neuroscience, 1983•karger.comA theoretical discussion on the correlation between residual enzyme activities in inherited
enzyme deficiencies and the development of neurological disorders is presented, based on
the kinetic analysis of a simple model. Several metabolic diseases with wide spectra of
clinical presentation are discussed in relation to this model.
enzyme deficiencies and the development of neurological disorders is presented, based on
the kinetic analysis of a simple model. Several metabolic diseases with wide spectra of
clinical presentation are discussed in relation to this model.
Abstract
A theoretical discussion on the correlation between residual enzyme activities in inherited enzyme deficiencies and the development of neurological disorders is presented, based on the kinetic analysis of a simple model. Several metabolic diseases with wide spectra of clinical presentation are discussed in relation to this model.
Karger