Strong increase in hydroxy fatty acids derived from linoleic acid in human low density lipoproteins of atherosclerotic patients
W Jira, G Spiteller, W Carson, A Schramm - Chemistry and physics of lipids, 1998 - Elsevier
Linoleic acid is the most abundant fatty acid in human low density lipoproteins (LDL).
Oxidation of LDL transforms linoleic acid to hydroperoxyderivatives. These are converted to
9-hydroxy-10, 12-octadecadienoic acid (9-HODE) and 13-hydroxy-9, 11-octadecadienoic
acid (13-HODE). 9-HODE is much more abundant in oxidized LDL than other lipid
peroxidation products and therefore an indicator of lipid peroxidation (LPO). In this study the
9-HODE content in the LDL of 19 obviously healthy volunteers and 17 atherosclerotic …
Oxidation of LDL transforms linoleic acid to hydroperoxyderivatives. These are converted to
9-hydroxy-10, 12-octadecadienoic acid (9-HODE) and 13-hydroxy-9, 11-octadecadienoic
acid (13-HODE). 9-HODE is much more abundant in oxidized LDL than other lipid
peroxidation products and therefore an indicator of lipid peroxidation (LPO). In this study the
9-HODE content in the LDL of 19 obviously healthy volunteers and 17 atherosclerotic …