[PDF][PDF] Involvement of alpha-2 adrenergic receptor subtypes in hyperglycemia.
I Angel, R Niddam, SZ Langer - Journal of Pharmacology and …, 1990 - Citeseer
I Angel, R Niddam, SZ Langer
Journal of Pharmacology and Experimental Therapeutics, 1990•CiteseerAlpha-2 adrenoceptor stimulation induces in the mouse a hyperglycemic response which is
accompanied by a concomitant inhibition of insulin secretion. To test the possibility that one
of the postulated subtypes of alpha-2 adrenoceptors is preferentially implicated in this
response, we compared the interaction of several drugs with known selectivity toward a! pha-
2A or alpha-
accompanied by a concomitant inhibition of insulin secretion. To test the possibility that one
of the postulated subtypes of alpha-2 adrenoceptors is preferentially implicated in this
response, we compared the interaction of several drugs with known selectivity toward a! pha-
2A or alpha-
Abstract
Alpha-2 adrenoceptor stimulation induces in the mouse a hyperglycemic response which is accompanied by a concomitant inhibition of insulin secretion. To test the possibility that one of the postulated subtypes of alpha-2 adrenoceptors is preferentially implicated in this response, we compared the interaction of several drugs with known selectivity toward a! pha-2A or alpha-
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