Cholecystokinin (CCK) has emerged as an important mammalian neuropeptide, localized in
peripheral organs and in the central nervous system. This review presents an overview of
the molecular aspects of CCK peptides and CCK receptors, the anatomical distribution of
CCK, the neurophysiological actions of CCK, release of CCK and effects of CCK on release
of other neurotransmitters, and the actions of CCK on digestion, feeding, cardiovascular
function, respiratory function, neurotoxicity and seizures, cancer cell proliferation, analgesia …