Immunoreceptor tyrosine-based inhibition motifs
Cells that are activated following ligation of receptors bearing immunoreceptor tyrosine-
based activation motifs (ITAMs) can be negatively regulated by other receptors bearing
immunoreceptor tyrosine-based inhibition motifs (ITIMs). Here, Eric Vivier and Marc Daëron
propose a structural and functional definition of ITIMs.
based activation motifs (ITAMs) can be negatively regulated by other receptors bearing
immunoreceptor tyrosine-based inhibition motifs (ITIMs). Here, Eric Vivier and Marc Daëron
propose a structural and functional definition of ITIMs.
Abstract
Cells that are activated following ligation of receptors bearing immunoreceptor tyrosine-based activation motifs (ITAMs) can be negatively regulated by other receptors bearing immunoreceptor tyrosine-based inhibition motifs (ITIMs). Here, Eric Vivier and Marc Daëron propose a structural and functional definition of ITIMs.
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