[HTML][HTML] Both iron deficiency and daily iron supplements increase lipid peroxidation in rats

MD Knutson, PB Walter, BN Ames, FE Viteri - The Journal of nutrition, 2000 - Elsevier
Numerous studies have shown that iron-loaded diets increase markers of lipid peroxidation
in rats, but few have addressed the effects of oral iron supplements on these markers. We
investigated the effects of daily and intermittent iron supplements on iron and vitamin E
status, and lipid peroxidation. Iron supplements were administered in doses equivalent to
those often given to pregnant women in the developing world. In Study 1, iron-deficient (D)
and iron-normal (N) rats were fed either 0 or 8000 μg of supplemental iron daily for 21 d. In …