[HTML][HTML] Multiple sclerosis: a coordinated immunological attack against myelin in the central nervous system

L Steinman - Cell, 1996 - cell.com
Cell, 1996cell.com
Multiple sclerosis (MS) is the most common autoimmune disease involving the nervous
system. In the United States∼ 250,000 individuals suffer from MS. The first clinical signs of
MS typically begin in young adulthood, and women with the disease outnumber men 2: 1.
The cause of the disease is unknown, but genetic factors are important. The concordance
rate among monozygotic twins is 30%, a 10-fold increase over dizygotic twins or first-degree
relatives (
Multiple sclerosis (MS) is the most common autoimmune disease involving the nervous system. In the United States∼ 250,000 individuals suffer from MS. The first clinical signs of MS typically begin in young adulthood, and women with the disease outnumber men 2: 1. The cause of the disease is unknown, but genetic factors are important. The concordance rate among monozygotic twins is 30%, a 10-fold increase over dizygotic twins or first-degree relatives (
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