[HTML][HTML] Co-signaling molecules of the B7-CD28 family in positive and negative regulation of T lymphocyte responses
S Wang, L Chen - Microbes and infection, 2004 - Elsevier
Co-signaling molecules in the B7-CD28 family have been intensively studied over the past
decade and have brought much excitement to the field of immune regulation. The discovery
of new functions for the classical pathways CD80/CD86/CD28/CTLA-4 and the identification
of novel pathways of the family, including B7-H1/B7-DC/PD-1, B7-H2/ICOS, B7-H3, B7-H4
and BTLA, are greatly broadening our understanding of the control of T cell-mediated
immune responses and tolerance.
decade and have brought much excitement to the field of immune regulation. The discovery
of new functions for the classical pathways CD80/CD86/CD28/CTLA-4 and the identification
of novel pathways of the family, including B7-H1/B7-DC/PD-1, B7-H2/ICOS, B7-H3, B7-H4
and BTLA, are greatly broadening our understanding of the control of T cell-mediated
immune responses and tolerance.