[HTML][HTML] Citrullination, a possible functional link between susceptibility genes and rheumatoid arthritis

ER Vossenaar, AJW Zendman, WJ Van Venrooij - Arthritis Res Ther, 2003 - Springer
ER Vossenaar, AJW Zendman, WJ Van Venrooij
Arthritis Res Ther, 2003Springer
Antibodies directed to citrullinated proteins (anti-cyclic citrullinated peptide) are highly
specific for rheumatoid arthritis (RA). Recent data suggest that the antibodies may be
involved in the disease process of RA and that several RA-associated genetic factors might
be functionally linked to RA via modulation of the production of anti-cyclic citrullinated
peptide antibodies or citrullinated antigens.
Abstract
Antibodies directed to citrullinated proteins (anti-cyclic citrullinated peptide) are highly specific for rheumatoid arthritis (RA). Recent data suggest that the antibodies may be involved in the disease process of RA and that several RA-associated genetic factors might be functionally linked to RA via modulation of the production of anti-cyclic citrullinated peptide antibodies or citrullinated antigens.
Springer