[HTML][HTML] Citrullination, a possible functional link between susceptibility genes and rheumatoid arthritis
ER Vossenaar, AJW Zendman, WJ Van Venrooij - Arthritis Res Ther, 2003 - Springer
ER Vossenaar, AJW Zendman, WJ Van Venrooij
Arthritis Res Ther, 2003•SpringerAntibodies directed to citrullinated proteins (anti-cyclic citrullinated peptide) are highly
specific for rheumatoid arthritis (RA). Recent data suggest that the antibodies may be
involved in the disease process of RA and that several RA-associated genetic factors might
be functionally linked to RA via modulation of the production of anti-cyclic citrullinated
peptide antibodies or citrullinated antigens.
specific for rheumatoid arthritis (RA). Recent data suggest that the antibodies may be
involved in the disease process of RA and that several RA-associated genetic factors might
be functionally linked to RA via modulation of the production of anti-cyclic citrullinated
peptide antibodies or citrullinated antigens.
Abstract
Antibodies directed to citrullinated proteins (anti-cyclic citrullinated peptide) are highly specific for rheumatoid arthritis (RA). Recent data suggest that the antibodies may be involved in the disease process of RA and that several RA-associated genetic factors might be functionally linked to RA via modulation of the production of anti-cyclic citrullinated peptide antibodies or citrullinated antigens.
Springer