[HTML][HTML] Immune regulation and graft survival in kidney transplant recipients are both enhanced by human leukocyte antigen matching

DS Rodriguez, E Jankowska-Gan, LD Haynes… - American journal of …, 2004 - Elsevier
We hypothesized that donor/recipient sharing of the human leukocyte antigen (HLA)
involved in allopeptide presentation to the T regulatory cell increases the incidence of
immune regulation, thus contributing to long-term graft survival. Peripheral blood
mononuclear cells (PBMC) were obtained from 40 living related donor (LRD) and 31
cadaver renal transplant recipients. The trans vivo delayed type hypersensitivity (DTH)
assay was used to assign patients to regulator, nonregulator, and sensitized categories. In a …