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Immune invasion
Huntington's disease (HD) is an incurable neurodegenerative disease caused by a mutation in the huntingtin gene (htt). Although most of the symptoms of HD are neurological, mutant HTT protein...
Published November 19, 2012
Scientific Show Stopper
Visualizing dopamine signaling in Angelman syndrome
Angelman syndrome (AS) is a developmental disorder characterized by intellectual disability, seizures, sleep disturbances, hand flapping, and a happy demeanor. It is caused by deletion or...
Published November 12, 2012
Scientific Show Stopper
A stunning view of the immune system
Immune responses take place throughout the body and require the migration of particular subsets of immune cells to precise locations. Brede et al. report the development of a microscopy...
Published November 12, 2012
Scientific Show Stopper
Choices
Mr. R is a 67-year-old Army veteran with metastatic lung cancer admitted with shortness of breath. His chest x-ray shows progression of his lung cancer. Three days ago, at his last appointment with...
Published November 6, 2012
Physician-Scientist Corner
Stuck together like glue
Integrins are proteins that connect the extracellular matrix to the cytoskeleton, mediating the attachment of cells to the surrounding tissue. The integrin α3β1, encoded by the gene ITGA3, is...
Published November 1, 2012
Scientific Show Stopper
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