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Shedding light on rhodopsin mutations
Retinitis pigmentosa (RP) is an inherited, degenerative eye disease that causes visual impairment and eventual blindness. RP is caused by mutations in eye photoreceptor rhodopsin. Zhang et al....
Published December 10, 2012
Scientific Show Stopper
Newborn neurons
Down syndrome (DS), a neurodevelopmental disorder caused by trisomy of chromosome 21, is the leading cause of inherited intellectual disability. The brains of patients with DS...
Published December 3, 2012
Scientific Show Stopper
Thomas Starzl
Today in the United States, more than 6,000 people a year receive a liver transplant, and since liver transplants have begun, over 200,000 patients have received this therapy. They survive today due to the efforts of a legendary scientist and surgeo...
Published December 3, 2012
Conversations with Giants in Medicine
A tale of two heme transporters
Erythropoiesis, or the production of red blood cells, is a tightly regulated process that is sensitive to cellular concentrations of heme. The protein FLVCR1 is a heme transporter and mutations...
Published November 26, 2012
Scientific Show Stopper
Parallel structure
The primary function of the kidneys is to filter the blood to remove waste and retain blood cells and proteins. Podocytes (shown in the panels above) are specialized kidney cells that form a...
Published November 26, 2012
Scientific Show Stopper
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