Aberrant blood vessel formation contributes to a wide variety of pathologies, and factors that regulate angiogenesis are attractive therapeutic targets. Endothelial and smooth muscle cell–derived neuropilin-like protein (ESDN) is a neuropilin-related transmembrane protein expressed in ECs; however, its potential effect on VEGF responses remains undefined. Here, we generated global and EC-specific
Lei Nie, Xiaojia Guo, Leila Esmailzadeh, Jiasheng Zhang, Abolfazl Asadi, Mark Collinge, Xuan Li, Jun-Dae Kim, Melissa Woolls, Suk-Won Jin, Alexandre Dubrac, Anne Eichmann, Michael Simons, Jeffrey R. Bender, Mehran M. Sadeghi
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