TY - JOUR AU - Riggs, B. Lawrence AU - Khosla, Sundeep AU - Melton, L. Joseph, III T1 - Better tools for assessing osteoporosis PY - 2012/12/03/ AB - Some 30 years ago, we applied the newly described method of dual photon absorptiometry (DPA) to demonstrate that osteoporotic women with vertebral fractures had lost substantially more bone from the vertebrae than controls. This opened a whole new field of research into the determinants of bone loss and fractures in the axial skeleton and set the stage for subsequent development of dual-energy x-ray absorptiometry (DXA) and quantitative computed tomography (QCT), which are now the standard methods for assessing osteoporosis severity and treatment efficacy. JF - The Journal of Clinical Investigation JA - J Clin Invest SN - 0021-9738 DO - 10.1172/JCI66746 VL - 122 IS - 12 UR - https://doi.org/10.1172/JCI66746 SP - 4323 EP - 4324 PB - The American Society for Clinical Investigation ER -