TY - JOUR AU - Murray, Jeffrey C. AU - Schutte, Brian C. T1 - Cleft palate: players, pathways, and pursuits PY - 2004/06/15/ AB - Cleft lip and palate is a common human birth defect, and its causes are being dissected through studies of human populations and through the use of animal models. Mouse models in particular have made a substantial contribution to our understanding of the gene pathways involved in palate development and the nature of signaling molecules that act in a tissue-specific manner at critical stages of embryogenesis. Related work has provided further support for investigating the role of common environmental triggers as causal covariates. JF - The Journal of Clinical Investigation JA - J Clin Invest SN - 0021-9738 DO - 10.1172/JCI22154 VL - 113 IS - 12 UR - https://doi.org/10.1172/JCI22154 SP - 1676 EP - 1678 PB - The American Society for Clinical Investigation ER -