Adenosine Triphosphatases of Rat Pancreatic Islets: COMPARISON WITH THOSE OF RAT KIDNEY

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Abstract

Electrolyte fluxes are fundamental to normal endocrine pancreatic function. Adenosine triphosphatases (ATPases) are enzyme systems believed to modulate electrolyte movements across membranes in a number of cell types. This study was undertaken to measure cation-dependent ATPases of rat pancreatic islets. In addition, we compared effects of substances which influence endocrine pancreatic function upon ATPases in homogenates of islets and kidney, the latter being a tissue which would not be expected to have a stimulus-secretion response to substances which activate islets.

Authors

Seymour R. Levin, Barry G. Kasson, June F. Driessen