@article{10.1172/JCI108407, author = {F Ciccimarra AND F S Rosen AND E Schneeberger AND E Merler}, journal = {The Journal of Clinical Investigation}, publisher = {The American Society for Clinical Investigation}, title = {Failure of heavy chain glycosylation of IgG in some patients with common, variable agammaglobulinemia.}, year = {1976}, month = {5}, volume = {57}, url = {https://www.jci.org/articles/view/108407}, pages = {1386-1390}, abstract = {Four patients with common, variable agammaglobulinemia were preveiously reported to have normal numbers of circulating B lymphocytes which synthesized normal amounts of IgG in tissue culture but failed to secrete the newly synthesized IgG. The B lymphocytes of these patients fail to incorporate [3H]mannose and/or [3H]glucosamine into newly synthesized IgG, whereas such incorporation appears to occur just before IgG secretion in cultures of normal B lymphocytes.}, number = {5}, doi = {10.1172/JCI108407}, url = {https://doi.org/10.1172/JCI108407}, }