[HTML][HTML] Obesity-induced inflammatory changes in adipose tissue
KE Wellen, GS Hotamisligil - The Journal of clinical …, 2003 - Am Soc Clin Investig
The Journal of clinical investigation, 2003•Am Soc Clin Investig
Obesity is associated with a state of chronic, low-grade inflammation. Two manuscripts in
this issue of the JCI (see the related articles beginning on pages 1796 and 1821) now report
that obese adipose tissue is characterized by macrophage infiltration and that these
macrophages are an important source of inflammation in this tissue. These studies prompt
consideration of new models to include a major role for macrophages in the molecular
changes that occur in adipose tissue in obesity.
this issue of the JCI (see the related articles beginning on pages 1796 and 1821) now report
that obese adipose tissue is characterized by macrophage infiltration and that these
macrophages are an important source of inflammation in this tissue. These studies prompt
consideration of new models to include a major role for macrophages in the molecular
changes that occur in adipose tissue in obesity.
Obesity is associated with a state of chronic, low-grade inflammation. Two manuscripts in this issue of the JCI (see the related articles beginning on pages 1796 and 1821) now report that obese adipose tissue is characterized by macrophage infiltration and that these macrophages are an important source of inflammation in this tissue. These studies prompt consideration of new models to include a major role for macrophages in the molecular changes that occur in adipose tissue in obesity.
The Journal of Clinical Investigation