Angiogenesis has critical roles in normal vascular development and in important
pathologies including cancer, wound healing and inflammation. This brief article will review
the angiogenic response induced by the vascular permeability factor/vascular endothelial
growth factor (VPF/VEGF) family of proteins and particularly VEGF‐A, thought to be the
single most important angiogenic factor. It will also review the steps and mechanisms by
which VEGF‐A induces the formation of new blood vessels and will provide an initial …