[HTML][HTML] Homo-and hetero-oligomerization of β-arrestins in living cells
Arrestins are important proteins, which regulate the function of serpentine heptahelical
receptors and contribute to multiple signaling pathways downstream of receptors. The
ubiquitous β-arrestins are believed to function exclusively as monomers, although self-
association is assumed to control the activity of visual arrestin in the retina, where this
isoform is particularly abundant. Here the oligomerization status of β-arrestins was
investigated using different approaches, including co-immunoprecipitation of epitope-tagged …
receptors and contribute to multiple signaling pathways downstream of receptors. The
ubiquitous β-arrestins are believed to function exclusively as monomers, although self-
association is assumed to control the activity of visual arrestin in the retina, where this
isoform is particularly abundant. Here the oligomerization status of β-arrestins was
investigated using different approaches, including co-immunoprecipitation of epitope-tagged …