Divergent roles of superoxide and nitric oxide in reduced-size liver ischemia and reperfusion injury: implications for partial liver transplantation
H Urakami, MB Grisham - Pathophysiology, 2006 - Elsevier
Hepatic resection with concomitant periods of ischemia and reperfusion (I/R) are required to
perform partial liver transplantation procedures such as split liver or living donor
transplantation. Although great progress has been made using these types of surgeries,
there remains substantial risk to both donors and recipients, with a significant number of
patients developing liver injury and failure during the course these operations. Therefore,
there is need to investigate the different mechanisms responsible for the tissue injury …
perform partial liver transplantation procedures such as split liver or living donor
transplantation. Although great progress has been made using these types of surgeries,
there remains substantial risk to both donors and recipients, with a significant number of
patients developing liver injury and failure during the course these operations. Therefore,
there is need to investigate the different mechanisms responsible for the tissue injury …