Serum angiopoietin-2 as a clinical marker for lung cancer
JH Park, KJ Park, YS Kim, SS Sheen, KS Lee, HN Lee… - Chest, 2007 - Elsevier
Background: Angiopoietins play a critical role in the angiogenesis related to tumor growth in
concert with vascular endothelial growth factor (VEGF), and enhanced expression of
angiopoietin-2 has been reported in lung cancer tissue. Methods: Patients with lung cancer
(n= 136) and healthy volunteers (n= 40) were enrolled. Serum angiopoietin-2 and VEGF
concentrations were measured using enzyme-linked immunosorbent assay. Results:
Patients with lung cancer had higher serum angiopoietin-2 (2,046.3±1,171.3 pg/mL vs …
concert with vascular endothelial growth factor (VEGF), and enhanced expression of
angiopoietin-2 has been reported in lung cancer tissue. Methods: Patients with lung cancer
(n= 136) and healthy volunteers (n= 40) were enrolled. Serum angiopoietin-2 and VEGF
concentrations were measured using enzyme-linked immunosorbent assay. Results:
Patients with lung cancer had higher serum angiopoietin-2 (2,046.3±1,171.3 pg/mL vs …