Trophic and protective actions of brain-derived neurotrophic factor on striatal DARPP-32-containing neurons in vitro
N Nakao, P Brundin, K Funa, O Lindvall… - Developmental brain …, 1995 - Elsevier
We have examined the effects of either brain-derived neurotrophic factor (BDNF), the BB-
isoform of platelet-derived growth factor (PDGF-BB), or a combination of these growth factors
on the survival and the morphological development of embryonic striatal neurons grown
under serum-free culture conditions. Striatal neurons were identified using
immunocytochemistry for “dopamine-and adenosine 3′: 5′-monophosphate-regulated
phosphoprotein with a molecular weight of 32 kilodalton”(DARPP-32). BDNF and PDGF-BB …
isoform of platelet-derived growth factor (PDGF-BB), or a combination of these growth factors
on the survival and the morphological development of embryonic striatal neurons grown
under serum-free culture conditions. Striatal neurons were identified using
immunocytochemistry for “dopamine-and adenosine 3′: 5′-monophosphate-regulated
phosphoprotein with a molecular weight of 32 kilodalton”(DARPP-32). BDNF and PDGF-BB …