Risperidone and cognitive function in children with disruptive behavior disorders

GJ Pandina, R Bilder, PD Harvey, RSE Keefe… - Biological …, 2007 - Elsevier
BACKGROUND: Effects of risperidone on cognitive function in children with disruptive
behavior disorders (DBDs) and subaverage intelligence quotient (IQ) were assessed.
METHODS: Data from two 6-week, double-blind, placebo-controlled studies (n= 228) were
combined, as were three 1-year, open-label studies (n= 688). Patients with DBDs and
subaverage IQ, 5 to14 years, received placebo or risperidone. 02 to. 06 mg/kg/day.
Cognitive measures included the Continuous Performance Task (CPT) and Verbal Learning …