Functional neuroimaging of social cognition in pervasive developmental disorders: a brief review
A Di Martino, FX Castellanos - … of the New York Academy of …, 2003 - Wiley Online Library
Annals of the New York Academy of Sciences, 2003•Wiley Online Library
An emerging literature on the neuroanatomical correlates of social cognition in pervasive
developmental disorders is reviewed. Studies conducted with high‐functioning adults with
autism or Asperger's syndrome highlight patterns of decreased activation in ventromedial
prefrontal cortex, temporo‐parietal junction, amygdala, and periamygdaloid cortex, along
with aberrantly increased activation in primary sensory cortices. Future studies should
extend these important initial results to younger and more severely affected subjects.
developmental disorders is reviewed. Studies conducted with high‐functioning adults with
autism or Asperger's syndrome highlight patterns of decreased activation in ventromedial
prefrontal cortex, temporo‐parietal junction, amygdala, and periamygdaloid cortex, along
with aberrantly increased activation in primary sensory cortices. Future studies should
extend these important initial results to younger and more severely affected subjects.
Abstract: An emerging literature on the neuroanatomical correlates of social cognition in pervasive developmental disorders is reviewed. Studies conducted with high‐functioning adults with autism or Asperger's syndrome highlight patterns of decreased activation in ventromedial prefrontal cortex, temporo‐parietal junction, amygdala, and periamygdaloid cortex, along with aberrantly increased activation in primary sensory cortices. Future studies should extend these important initial results to younger and more severely affected subjects.
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