Use of diethylstilbestrol to prevent fetal loss from complications of late pregnancy

OW Smith, GVS Smith - New England Journal of Medicine, 1949 - Mass Medical Soc
OW Smith, GVS Smith
New England Journal of Medicine, 1949Mass Medical Soc
THE present communication deals with further progress in a clinical evaluation of our
concept concerning the action of diethylstilbestrol in human pregnancy. Analyses of results
in 632 pregnancies during which this drug was given in the manner recommended by us
have been reported. 1 In 491 of these cases stilbestrol was administered for the prevention
or treatment of abortion. A preliminary report was included, however, upon its use in 95
patients for the purpose of preventing complications of late pregnancy. These 95 cases are …
THE present communication deals with further progress in a clinical evaluation of our concept concerning the action of diethylstilbestrol in human pregnancy. Analyses of results in 632 pregnancies during which this drug was given in the manner recommended by us have been reported.1 In 491 of these cases stilbestrol was administered for the prevention or treatment of abortion. A preliminary report was included, however, upon its use in 95 patients for the purpose of preventing complications of late pregnancy. These 95 cases are included in the present study of a total of 180 women in whom the indication for therapy . . .
The New England Journal Of Medicine