The effects of vasopressin (VP), VP fragments and propres-sophysin glycopeptide on
neuronal activities in the septum-hippocampus complex of rats were studied in vitro and in
vivo. The frequency of the hippocampus theta rhythm in Brattleboro rats homozygous for
diabetes insipidus was significantly slower than that of heterozygous litter mates and normal
rats. Intracerebroventricular micro-injection of des-glycine-amide vasopressin corrected for
several hours the frequency deficit of the theta rhythm in the homozygous Brattleboro rats …