T type 1/type 2 subsets balance in B-cell chronic lymphocytic leukemia—the three-color flow cytometry analysis
M Podhorecka, A Dmoszynska, J Rolinski, E Wasik - Leukemia research, 2002 - Elsevier
The impairments in immune cell functions as well as changes in cytokine network are the
cause of malignant cell accumulation and secondary immune deficiencies in B-cell chronic
lymphocytic leukemia (B-CLL). To broaden the knowledge of immune system in B-CLL we
tried to evaluate the Th1/Th2 and Tc1/Tc2 balance in B-CLL patients in comparison with
healthy individuals and changes of this pattern during disease progression. The three-color
flow cytometry technique was used to analyze IL-4 and IFNγ expression in peripheral blood …
cause of malignant cell accumulation and secondary immune deficiencies in B-cell chronic
lymphocytic leukemia (B-CLL). To broaden the knowledge of immune system in B-CLL we
tried to evaluate the Th1/Th2 and Tc1/Tc2 balance in B-CLL patients in comparison with
healthy individuals and changes of this pattern during disease progression. The three-color
flow cytometry technique was used to analyze IL-4 and IFNγ expression in peripheral blood …