[HTML][HTML] The cold plate as a test of nociceptive behaviors: description and application to the study of chronic neuropathic and inflammatory pain models
L Jasmin, L Kohan, M Franssen, G Janni, JR Goff - Pain, 1998 - Elsevier
A cold plate apparatus was designed to test the responses of unrestrained rats to low
temperature stimulation of the plantar aspect of the paw. At plate temperatures of 10° C and
5° C, rats with either chronic constriction injury (CCI) of the sciatic nerve or complete
Freund's adjuvant (CFA) induced inflammation of the hindpaw displayed a stereotyped
behavior. Brisk lifts of the treated hindpaw were recorded, while no evidence of other
nociceptive behaviors could be discerned. The most consistent responses were obtained …
temperature stimulation of the plantar aspect of the paw. At plate temperatures of 10° C and
5° C, rats with either chronic constriction injury (CCI) of the sciatic nerve or complete
Freund's adjuvant (CFA) induced inflammation of the hindpaw displayed a stereotyped
behavior. Brisk lifts of the treated hindpaw were recorded, while no evidence of other
nociceptive behaviors could be discerned. The most consistent responses were obtained …