Recombinant human interleukin 5 is a selective activator of human eosinophil function.
The Journal of experimental medicine, 1988•europepmc.org
BriefDefinitive Report Page 1 RECOMBINANT HUMAN INTERLEUKIN 5 IS A SELECTIVE
ACTIVATOR OF HUMAN EOSINOPHIL FUNCTION BY ANGEL F. LOPEZ,* COLIN J.
SANDERSON,$ JENNIFER R. GAMBLE,* HUGH D. CAMPBELL§ IAN G. YOUNG,4 AND
MATHEW A. VADAS* From *The Division of Human Immunology, Institute ofMedical and
Veterinary Science, Adelaide, South Australia; the $National Institutefor Medical Research, The
Ridgeway, Mill Hill, London NW7 IAA, United Kingdom; and the §Medical Molecular Biology …
ACTIVATOR OF HUMAN EOSINOPHIL FUNCTION BY ANGEL F. LOPEZ,* COLIN J.
SANDERSON,$ JENNIFER R. GAMBLE,* HUGH D. CAMPBELL§ IAN G. YOUNG,4 AND
MATHEW A. VADAS* From *The Division of Human Immunology, Institute ofMedical and
Veterinary Science, Adelaide, South Australia; the $National Institutefor Medical Research, The
Ridgeway, Mill Hill, London NW7 IAA, United Kingdom; and the §Medical Molecular Biology …
Abstract
Human rIL-5 was found to selectively stimulate morphological changes and the function of human eosinophils. This molecule is thus a prime candidate for the selective eosinophilia and eosinophil activation seen in disease.
europepmc.org