Human cholinergic basal forebrain: chemoanatomy and neurologic dysfunction

EJ Mufson, SD Ginsberg, MD Ikonomovic… - Journal of chemical …, 2003 - Elsevier
The human cholinergic basal forebrain (CBF) is comprised of magnocellular hyperchromic
neurons within the septal/diagonal band complex and nucleus basalis (NB) of Meynert. CBF
neurons provide the major cholinergic innervation to the hippocampus, amygdala and
neocortex. They play a role in cognition and attentional behaviors, and are dysfunctional in
Alzheimer's disease (AD). The human CBF displays a continuum of large cells that contain
various cholinergic markers, nerve growth factor (NGF) and its cognate receptors, calbindin …