Alzheimer disease in 2020
DM Holtzman, E Mandelkow… - Cold Spring …, 2012 - perspectivesinmedicine.cshlp.org
DM Holtzman, E Mandelkow, DJ Selkoe
Cold Spring Harbor perspectives in medicine, 2012•perspectivesinmedicine.cshlp.orgRemarkable advances in unraveling the biological underpinnings of Alzheimer disease (AD)
have occurred during the last 25 years. Despite this, we have made only the smallest of
dents in the development of truly disease-modifying treatments. What will change over the
next 10 years? While the answer is not clear, we make several predictions on the state of the
field in 2020, based on the rich knowledge described in the other contributions in this
collection. As such, our predictions represent some of the principal unresolved questions …
have occurred during the last 25 years. Despite this, we have made only the smallest of
dents in the development of truly disease-modifying treatments. What will change over the
next 10 years? While the answer is not clear, we make several predictions on the state of the
field in 2020, based on the rich knowledge described in the other contributions in this
collection. As such, our predictions represent some of the principal unresolved questions …
Remarkable advances in unraveling the biological underpinnings of Alzheimer disease (AD) have occurred during the last 25 years. Despite this, we have made only the smallest of dents in the development of truly disease-modifying treatments. What will change over the next 10 years? While the answer is not clear, we make several predictions on the state of the field in 2020, based on the rich knowledge described in the other contributions in this collection. As such, our predictions represent some of the principal unresolved questions that we believe deserve special investigative attention in the coming decade.
perspectivesinmedicine.cshlp.org