IMP-3 is differentially expressed in normal and neoplastic lymphoid tissue

RL King, T Pasha, MR Roullet, PJ Zhang, A Bagg - Human pathology, 2009 - Elsevier
IMP-3 is a member of the insulin-like growth factor II mRNA binding protein (IMP) family of
proteins that play a role in RNA trafficking and stabilization and cell growth and migration
during embryogenesis but which are down-regulated in adult tissue. However, IMP-3 has
recently been shown to be overexpressed in several epithelial malignancies, with increased
expression correlating with aggressive behavior. To our knowledge, there is no published
literature evaluating IMP-3 in lymphoid tissue. Accordingly, we immunohistochemically …