Calcium and age in fibroblasts from control subjects and patients with cystic fibrosis
BL Shapiro, LFH Lam - Science, 1982 - science.org
BL Shapiro, LFH Lam
Science, 1982•science.orgIntracellular calcium increases significantly as human fibroblasts age in culture. The calcium
increase occurs 5 to 6 weeks (passages) earlier and is significantly greater in fibroblasts
from subjects with cystic fibrosis in comparison with cells from control subjects. Intracellular
calcium, which is thought to be a pathogenetic factor in cystic fibrosis, may also be a
meaningful marker in cell aging.
increase occurs 5 to 6 weeks (passages) earlier and is significantly greater in fibroblasts
from subjects with cystic fibrosis in comparison with cells from control subjects. Intracellular
calcium, which is thought to be a pathogenetic factor in cystic fibrosis, may also be a
meaningful marker in cell aging.
Intracellular calcium increases significantly as human fibroblasts age in culture. The calcium increase occurs 5 to 6 weeks (passages) earlier and is significantly greater in fibroblasts from subjects with cystic fibrosis in comparison with cells from control subjects. Intracellular calcium, which is thought to be a pathogenetic factor in cystic fibrosis, may also be a meaningful marker in cell aging.
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