Pediatric acute-onset neuropsychiatric syndrome

TK Murphy, DM Gerardi, JF Leckman - Psychiatric Clinics, 2014 - psych.theclinics.com
Pediatric autoimmune neuropsychiatric disorder associated with Streptococcus (PANDAS) is
characterized by an abrupt (24–48 hours) onset of obsessivecompulsive disorder (OCD)
and/or tics. Associated symptoms include emotional lability, separation anxiety, deterioration
in handwriting, poor attention, and attention deficit/hyperactivity disorder (ADHD)-like
impulsivity, deteriorating visual-spatial abilities, math and reading deficits, and enuresis (Box
1). 1 Neuropsychiatric symptoms tend to emerge 7 to 14 days after a group A streptococcal …