Relationship of movements and behaviors to Group A Streptococcus infections in elementary school children

TK Murphy, LA Snider, PJ Mutch, E Harden… - Biological …, 2007 - Elsevier
BACKGROUND: Pediatric Autoimmune Neuropsychiatric Disorders Associated with
Streptococcus (PANDAS) research is based on the hypothesis that infections trigger
changes in behavior and movement in children. METHODS: We enrolled 693 children (ages
3 to 12 years) into a systematic, longitudinal study. Data were collected monthly for 8 months
(October–May) to determine point prevalence of Group A Streptococcal (GAS) infections,
tics, behavior, and choreiform movements. Simultaneous throat cultures were obtained, and …