A MicroRNA expression profile defining the invasive bladder tumor phenotype
MF Wszolek, KM Rieger-Christ, PA Kenney… - … Oncology: Seminars and …, 2011 - Elsevier
OBJECTIVE: The purpose of this study was to identify microRNA (miRNA) involved in the
transition between the noninvasive and invasive urothelial carcinoma of the bladder (UCB)
phenotype. METHODS: Differential expression of miRNA was identified in a microarray
format between noninvasive and invasive UCB cell lines and confirmed using quantitative
reverse transcriptase-polymerase chain reaction (qRT-PCR) within this cell panel.
Normalization of qRT-PCR with miR-222 was established from the microarray data and …
transition between the noninvasive and invasive urothelial carcinoma of the bladder (UCB)
phenotype. METHODS: Differential expression of miRNA was identified in a microarray
format between noninvasive and invasive UCB cell lines and confirmed using quantitative
reverse transcriptase-polymerase chain reaction (qRT-PCR) within this cell panel.
Normalization of qRT-PCR with miR-222 was established from the microarray data and …