Tenascins: regulation and putative functions during pathological stress
R Chiquet‐Ehrismann, M Chiquet - The Journal of Pathology: A …, 2003 - Wiley Online Library
R Chiquet‐Ehrismann, M Chiquet
The Journal of Pathology: A Journal of the Pathological Society of …, 2003•Wiley Online LibraryIn this review, we discuss the structure and function of the extracellular matrix protein family
of tenascins with emphasis on their involvement in human pathologies. The article is divided
into the following sections: Introduction: the tenascin family of extracellular matrix proteins;
Structural roles: tenascin‐X deficiency and Ehlers–Danlos syndrome; Tenascins as
modulators of cell adhesion, migration, and growth; Role of tenascin‐C in inflammation;
Regulation of tenascins by mechanical stress: implications for wound healing and …
of tenascins with emphasis on their involvement in human pathologies. The article is divided
into the following sections: Introduction: the tenascin family of extracellular matrix proteins;
Structural roles: tenascin‐X deficiency and Ehlers–Danlos syndrome; Tenascins as
modulators of cell adhesion, migration, and growth; Role of tenascin‐C in inflammation;
Regulation of tenascins by mechanical stress: implications for wound healing and …
Abstract
In this review, we discuss the structure and function of the extracellular matrix protein family of tenascins with emphasis on their involvement in human pathologies. The article is divided into the following sections: Introduction: the tenascin family of extracellular matrix proteins; Structural roles: tenascin‐X deficiency and Ehlers–Danlos syndrome; Tenascins as modulators of cell adhesion, migration, and growth; Role of tenascin‐C in inflammation; Regulation of tenascins by mechanical stress: implications for wound healing and regeneration; Association of tenascin‐C with cancer: antibodies as diagnostic and therapeutic tools; Conclusion and perspectives. Copyright © 2003 John Wiley & Sons, Ltd.
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